LEGAL REFERENCES

REGULATORY INFORMATION
MEDICAL REFERENCES
S1
Nazene® Z. Each 1 ml spray contains oxymetazoline hydrochloride 0,5 mg; zinc sulphate 0,015 mg. Ref. No. H1501 (Act 101/1965).
S1
Nazene Adult Nasal Metered Spray. Each 1 ml of the solution contains oxymetazoline hydrochloride 0,50 mg. Reg. No. A39/16.1/0211. For full prescribing information refer to the professional information approved by SAHPRA. Adcock Ingram Limited Co. Reg. No. 1949/034385/06. Private Bag X69, Bryanston, 2021, South Africa. Customer care: 0860 ADCOCK/232625 www.adcock.com
  1. Nazene® Z Nasal Spray Professional Information, February 2019.
  2. Druce, H. M. et al Topical nasal decongestant oxymetazoline (0,05%) provides relief of nasal symptoms for 12 hours. Rhinology 56, 1-8 (2018).
  3. What Causes a Stuffy Nose? [Internet]. Healthline. 2016. [Cited 2025 March 12]. Available from: https://www.healthline.com/health/nasalcongestion#causes.
  4. Cleveland Clinic. Nasal Congestion (Stuffy Nose): What It Is, Causes & Treatment [Internet]. Cleveland Clinic. 2022. [Cited 2025 March 12]. Available from: https://my.clevelandclinic.org/health/diseases/17980-nasal-congestion.
  5. Corren J, Storms W, Bernstein J, Berger W, Nayak A, Sacks H. Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis. Clinical Therapeutics. 2005 May;27(5):543–53. DOI: 10.1016/j.clinthera.2005.04.012.
  6. Nazene® Z Adult Nasal Metered Spray Professional Information, 2016.
  7. MD BB. Can Air Conditioning Make Sinus Problems Worse? [Internet]. Indiana Sinus Centers |. 2025 [cited 2025 Oct 3]. Available from: https://indianasinuscenters.com/can-air-conditioning-make-sinus-problems-worse/